Affecting of vitamin D administration on mRNA expression of Treg/Th17 axis.
Phase 3
Recruiting
- Conditions
- Multiple Sclerosis.Multiple sclerosis
- Registration Number
- IRCT20100407003655N4
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
The ability to give blood sample
Tendency to take part in the study
having 20-40 years old
Verifying MS diseases by a neurologist expert
No receiving of vitamin D supplementation in the last 2 months
Exclusion Criteria
Having malabsorption
Consumption of medicine that interact with Vitamin D absorption
Catching chronic and immune system diseases
Consumption of Ca & Vitamin D supplementation
pregnancy and lactation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IL-17A. Timepoint: Before and After supplementation. Method of measurement: Real time - PCR.;TGF-B. Timepoint: Before and After supplementation. Method of measurement: Real time - PCR.;Vitamin D. Timepoint: Before and After supplementation. Method of measurement: ECL.
- Secondary Outcome Measures
Name Time Method