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Clinical Trials/NCT05407935
NCT05407935
Completed
N/A

Early Phase Clinical Trial to Test the Feasibility of an ACT-based Physical Activity Promotion Program for Adults With Depressive Symptoms

Brown University1 site in 1 country75 target enrollmentAugust 16, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Physical Inactivity
Sponsor
Brown University
Enrollment
75
Locations
1
Primary Endpoint
Change in Accelerometry
Status
Completed
Last Updated
8 months ago

Overview

Brief Summary

The goal of the proposed project is to conduct a feasibility clinical trial comparing group-based acceptance and commitment therapy for physical activity, (ACT; ACTivity) to a time- and attention-matched standard PA intervention (i.e., PA education, goal-setting, and self-monitoring) plus relaxation training comparison condition (Relaxercise) among 60 low-active adults (ages 18-65) with elevated depressive symptoms. Participants will be randomized to treatment condition, followed for 6 months, including the 8-week treatment. Participants will be randomized 1:1 to treatment condition, followed for 6 months, including the 8-week treatment, and receive a 6-month YMCA membership to equate access to PA facilities.

Registry
clinicaltrials.gov
Start Date
August 16, 2022
End Date
May 30, 2025
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Elevated depressive symptoms (CES-D score of greater than or equal to 10)
  • Low-active (less than 60 minutes per week of moderate intensity PA)
  • Willing and able to attend weekly virtual video sessions via Zoom

Exclusion Criteria

  • Regular mindfulness meditation practice (more than once per week)
  • Body Mass Index (BMI) less than 18.5 or greater than 40
  • History or presence of any condition that may limit or substantially increase the risks of physical activity
  • Active suicidal thoughts or behaviors
  • Currently participating in any exercise or weight-loss research studies
  • Household member is participating in this study
  • Does not have a Rhode Island mailing address OR if only Rhode Island mailing address is a PO box
  • Unable to receive materials in the mail at residential mailing address
  • Does not plan to live in Rhode Island for the next 6 months
  • Unable to speak, read, and/or write fluently in English

Outcomes

Primary Outcomes

Change in Accelerometry

Time Frame: Baseline, Post-Treatment (8 weeks), 6-months

Minutes of physical activity weighted by intensity, expressed in metabolic equivalent (MET) minutes per week as determined by accelerometers (Actigraph \[model wGT3x-BT\]) worn during one-week periods.

Secondary Outcomes

  • Change in Self-report physical activity (Godin)(Baseline, Mid-Treatment (4 weeks) Post-Treatment (8 weeks), 6-months)
  • Change in Self-reported depression symptoms (CES-D)(Baseline, Mid-Treatment (4 weeks) Post-Treatment (8 weeks), 6-months)

Study Sites (1)

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