To compare low cost treatment regimen with standard treatment in patients with hepatorenal syndrome
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Hepatorenal syndrome
- Registration Number
- CTRI/2011/07/001860
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
All patients with cirrhosis and HRS as defined by International ascites club diagnostic criteria
Exclusion Criteria
Active GI bleed, Presence of sepsis or hypotension requiring inotropic support, Known underlying pre-existing primary renal disease, Ischemic heart disease, Hepatocellular carcinoma, Diabetes mellitus, Portal vein thrombosis, HVOTO, Tubercular peritonitis, Lack of informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Proportion of patients with improvement in urine output, serum creatinine and PRA by 50% <br/ ><br>2) Survival among the two treatment regimesTimepoint: 1) day 5 and 15 between two treatment groups <br/ ><br>2) day 7, 14, 4 weeks, 12 weeks, 24 weeks <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1)Recurrence of HRS requiring hospitalization <br/ ><br>2) Side effect of therapy <br/ ><br>3) Cost of therapyTimepoint: 1) 6 months