Efficacy of Platelet Rich Plasma and fractional co2 laser in treatment of acne scar of face
- Conditions
- acne scar.scar cndition and fibrosis of skin
- Registration Number
- IRCT2014080218648N1
- Lead Sponsor
- Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
1.Patients who have polymorphic and mixed acne scar (dominantly rolling and boxcar types ,less than %20 ice pick type and no hypertrophic or keloid type) 2.Patients who dont have other skin disease 3.Patients who have skin types 3-5 in fitzpatrick scale 4. Willingness for participation in the study and signing the consent form.
Exclusion criteria:1.Known allergic reaction to components of study treatment that leads to unfinished study 2.Patient is unwilling to continue the study 3.Co-treatment with other methods 4.History of keloid formation 5.Any kind of active inflammation 6. Oral isotretinoin use within the preceding 6 months 7. Diabetes, collagen vascular disease 8. Ablative or nonablative laser skin resurfacing within the preceding 12 months, 9.Pregnancy or lactation 10.If patient doesnt follow the study .
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Atrophic scar of acne. Timepoint: Before and after the intervention. Method of measurement: Photography of scar before beginning ,1 month after first session of treatment and 4 months after second session of treatment.
- Secondary Outcome Measures
Name Time Method Clinical improvement of scar. Timepoint: 1 month after first session of treatment and 4 months after second session of treatment. Method of measurement: Self-assessment by the patients and visual analogue scale.;Treatment associated adverse events(erythema and edema). Timepoint: days 0, 2, 4, 6, 8, 15, and 30 after each session of treatment. Method of measurement: serial photography,inspection by dermatologist and visual analogue scale.;Patients satisfaction. Timepoint: 1 month after first session of treatment and 4 months after second session of treatment. Method of measurement: Quartile scale.