Enhancing Retention in PMTCT/MNCH Services and Facility Delivery in Tabora, Tanzania
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- HIV
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
- Enrollment
- 1505
- Locations
- 1
- Primary Endpoint
- Early identification of HEI at Reproductive and Child Health (RCH) Clinic
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The goal of this proposed intervention study is to increase the proportion of HIV positive and HIV negative pregnant women who deliver in a facility, the proportion of HIV exposed infants (HEI) who receive nevirapine (NVP) within 48 hours of delivery, and the proportion of HEI who are bled for HIV polymerase chain reaction (PCR) deoxyribonucleic acid (DNA) testing within 8 weeks of age.
Detailed Description
Following a formative phase I, we propose in phase II to implement a three-group cluster-randomized study to test the effectiveness of short message service (SMS) reminders and notifications, \[mobile health or mhealth\] (group 1) and the combined effectiveness of SMS reminders/notifications and cash transfers (group 2) compared to the standard prevention of mother-to-child transmission (of HIV)/maternal, neonatal and child health, (PMTCT/MNCH) practices (group 3).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Known or recently diagnosed HIV-positive in ANC or; Tested HIV-negative at ANC
- •Plans to deliver in facility catchment area
- •18 years or older
- •Able and willing to provide consent
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Early identification of HEI at Reproductive and Child Health (RCH) Clinic
Time Frame: 1 year
Proportion of HEI identified early (48 hours,3 and 7 days) at RCH clinic
Antenatal care (ANC) visits
Time Frame: 1 year
Proportion of pregnant women attending at least 4 ANC visits
Facility delivery
Time Frame: 1 year
Proportion of pregnant women delivering in a health facility
Post natal care (PNC) visits
Time Frame: 1 year
Proportion of post partum women attending PNC 48 hours, 3 and 7 days post delivery
Nevirapine (NVP) at delivery
Time Frame: 1 year
Proportion of HEI given NVP at delivery
Attendance for Early infant diagnosis (EID) of HIV
Time Frame: 1 year
Proportion of HIV-exposed infants (HEI) attending for early infant diagnosis of HIV (DBS collected) by 8 weeks
Secondary Outcomes
- Receipt of EID results(1 year)
- Time to receipt of EID results(1 year)
- Time to treatment(! year)
- HIV infected infants initiated on antiretroviral therapy (ART)(1 year)
- Time to EID(1 year)