Effect of parecoxib intravenous administered compared with bupivacaine local infiltration in post surgical pain management following total abdominal hysterectomy

Phase 4

Completed

• Conditions: patients undergoing total abdominal hysterrectomy; parecoxib; bupivacaine; PCA; total abdominal hysterctomy; pain score

• Registration Number: TCTR20150320001
• Lead Sponsor: Department of Obstetrics and Gynecology, Faculty of Medicine Ramathibodi Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-12-31
• Study Start: 2015-03-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 42

Inclusion Criteria

age 18-60 yr
undergoing total abdominal hysterrectomy
ASA status I-II

Exclusion Criteria

BMI > 30 kg/m2
known case or suspected OSA
history of MI or CHF
history of GI bleeding
drug allergy to parecoxib, NSAIDs, bupivacaine
mental or physical inability to use PCA
serum creatinine > 1.5 mg/dL
severe liver disease ( Child-Pugh Class C)
stroke

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pain score 2, 6, 10, 14, 26 hr after the operation asked patients for pain score in each time

Secondary Outcome Measures

Name	Time	Method
morphine consumption by PCA 2, 6, 10, 14, 26 hr after the operation record morphine consumption in each time