Parenteral parecoxib provides similar analgesic efficacy to single-shot sciatic nerve block after total knee arthroplasty when combined with continuous femoral nerve block

Phase 2

Completed

• Conditions: Total Knee Arthroplasty (TKA); Parecoxib; Total knee arthroplasty; Sciatic nerve block

• Registration Number: TCTR20150608001
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-10-04
• Study Start: 2015-06-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

- Adults undergoing unilateral TKA
- Written informed consent obtained

Exclusion Criteria

- Infection at the planned site of skin puncture, coagulopathy, known allergy to local anesthetics, and inability to operate a patient-controlled analgesia device (PCA). Patients with relative contraindications to intravenous parecoxib, such as coronary artery disease, cerebrovascular disease, asthma and severe renal function impairment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified