Vaginal Wound Infiltration Analgesia for Postoperative Pain After Laparoscopic Hysterectomy: a Randomized Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- Helsinki University Central Hospital
- Enrollment
- 81
- Primary Endpoint
- Postoperative pain scores
- Last Updated
- 9 years ago
Overview
Brief Summary
In cases of laparoscopic hysterectomy , women were randomized to two groups: ropivacaine ( vaginal wound infiltration analgesia) vs. control group. Results regarding postoperative pain and need of oxycodone.
Detailed Description
Women assigned to laparoscopic hysterectomy were randomly divided into two groups as regard surgery: a ropivacaine group (RG) (n=41) and a control group (CG) (n=40). General anesthesia and use of local anesthetics were standardized. Visual analog scale (VAS) scores for pain and side effects (nausea/vomiting) and the amount of postoperative analgesic used were recorded for 24 hours.
Investigators
Päivi Päkarinen
MD PhD
Helsinki University Central Hospital
Eligibility Criteria
Inclusion Criteria
- •The criteria for inclusion were scheduled laparoscopic hysterectomy
Exclusion Criteria
- •The exclusion Criteria were contraindications to any of the forms of medication used in the study (oxycodone, ketoprofen, paracetamol), language difficulties ( inability to understand and speak Finnish or Swedish)
Outcomes
Primary Outcomes
Postoperative pain scores
Time Frame: Change in 24 hours after surgery
Visual Analog Score (VAS) for pain. Physicians Global Assessment to measure quality of pain. 10-point VAS score for pain (0-10), 0 indicating no pain and 10 indicating unbearable pain at 1,3,6,12 and 24 h (hour) after surgery (Units on a Scale; 0-10).
Secondary Outcomes
- Complication(Up to one week)
- Nausea(Change in 24 hours after surgery.)
- Length of hospitalisation(Up to one week)
- The use of analgesics for postoperative pain(Change in 24 hours after surgery)
- Vomiting(Change in 24 hours after surgery.)