EUCTR2011-003293-93-NL进行中（未招募）不适用
Cyp3A4 metabolism before and after surgery induced weight loss in morbidly obese patients, using midazolam as a model drug - DEMO
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-20 Morbidly obese subjects scheduled for a gastric bypass surgery. We will stratify subjects to 4 weight groups: 100-120 kg; 120-145 kg; 145-170 kg; >170 kg
- •-Age 18-60 year old
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 20
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •-Prescription or use of either CYP3A4-activity inducing or decreasing medication.
- •-Use of product containing grapefruit, wild grape, banpeiyu, pomegranate, star fruit, black berry and wild grape within 2 weeks prior to the study.
- •-Pregnancy, breastfeeding
- •-Renal insufficiency
研究者
相似试验
已完成
不适用
Cyp3A4 metabolism before and after surgery induced weight loss in morbidly obese patients, using midazolam as a model drugobesity or overweight10017998NL-OMON39456Sint Antonius Ziekenhuis20
暂停
不适用
Perioperative metabolome changes in patients undergoing general anaesthesia for tumor surgeryGeneral anaesthesiaC25Malignant neoplasm of pancreasDRKS00016686niversitätsklinikum Heidelberg Klinik für Anästhesiologie30
进行中（未招募）
1 期
Preoperative supplementation of pancreatic enzymes for Whipple’s procedure for malignancies (PREPARE).EUCTR2018-000242-19-GBniversity Hospitals Southampton NHS Trust128
进行中（未招募）
1 期
MOU-2017-01locally advanced resectable oesophago-gastric adenocarcinoma (Siewert I – III) with T3N0, T4N0, T2 – T4N+, stage Ib – IIIcMedDRA version: 21.0Level: PTClassification code 10030137Term: Oesophageal adenocarcinomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)MedDRA version: 20.0Level: PTClassification code 10001150Term: Adenocarcinoma gastricSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2017-001264-38-SKMasarykuv onkologický ústav70
已完成
不适用
Perioperative changes of microbiome and metabolism in cardiac surgery patientsI25.1R65.2F05.8T81.1R57.2J95.1K56.7R65.1Atherosclerotic heart diseaseSystemic Inflammatory Response Syndrome of non-infectious origin without organ failureOther deliriumShock during or resulting from a procedure, not elsewhere classifiedAcute pulmonary insufficiency following thoracic surgeryIleus, unspecifiedSystemic Inflammatory Response Syndrome of infectious origin with organ failureSeptic shockDRKS00016493niversitätsklinikum Schleswig-Holstein Campus Kiel100