Comparison among different regimens of intravenous tranexamic acid for reducing blood transfusion in femoral neck fracture after hemiarthroplasty : A Randomized Controlled Trial
Phase 2
- Conditions
- Dose the comparison of different regimens of intravenous tranexamic acid can reduce blood transfusion in femoral neck fracture after hip hemiarthroplasty ?hip hemiarthroplasty,tranexamic acid
- Registration Number
- TCTR20200506007
- Lead Sponsor
- Department Orthopedic Surgery, Mahidol University Faculty of Medicine Siriraj Hospita
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Patients aged older than 60 years undergoing primary hip hemiarthroplasty for fracture neck of femur
Exclusion Criteria
- high energy trauma
- pathological fracture
- contraindication for tranexamic acid
- accidentally intraoperative fracture require revision femoral stem
- acetabulum pathology require covert to total hip arthroplasty
- bleeding disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood transfusion given perioperative and post operative day1-2 CBC
- Secondary Outcome Measures
Name Time Method Transfusion unit perioperative and post operative day1-2 CBC ,Intraoperative blood loss perioperative intraoperative blood loss by suction,Delta hemoglobin perioperative and post operative day1-2 CBC ,Total blood loss in 24,48 hr post operative day1-2 CBC ,Length of stay admision Length of stay,Postoperative complication admision, follow post op 2,6,12 weeks complication