Prolozone Therapy for Osteoarthritis of the Knee Study
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/11/059765
- Lead Sponsor
- Sri Madhusudan Sai Institute of Medical Sciences and Research,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Adult patients aged 40 years and above, who meet the American College of Rheumatology criteria for osteoarthritis (knee pain for most of the days of the previous month and osteophyte (s) at the joint line visible on X ray) 29, are willing to consent and have moderate-severe OAK.
Clinical Severity: Patients should have a mean score of 1.5 - 3.5 on WOMAC A sub score30, 31.
Radiological Severity of Osteoarthritis of the knee is based on the criteria defined by Kellgren and Lawrence, which grades OAK into 0-4 grades32. This study will be including Grade 3 and Grade 4 Osteoarthritis of the knee
Participants unwilling to provide consent
Patients with mild OAK
Participants with known history of drug allergy to bupivacaine, corticosteroid or lidocaine
Patients on anticoagulant or antiplatelet medication
Patients who have had a myocardial infraction in the last 6 months
Patients with secondary OAK (gout, RA, Psoriasis) or generalized osteoarthritis
Patients who have received intra articular steroids into any joint within 3 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method