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Interleukin 38 as a Biomarker for Metabolic Syndrome in Psoriatic Patients

Conditions
Psoriasis
Registration Number
NCT05076812
Lead Sponsor
Sohag University
Brief Summary

case control study to compare level of interleukin 38 in patients with psoriasis and patients with metabolic syndrome with healthy control subjects

Detailed Description

this case control study will measure plasma level of interleukin 38 in 4 groups of 24 subject, group one will have psoriatic patients, group 2 will have psoriatic patients with metabolic syndrome, group three will have patients with metabolic syndrome only, and group 4 will have healthy control subjects.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
96
Inclusion Criteria
  • specific to each group
Exclusion Criteria
  • Patient refusal. Age <18 years Pregnancy Lactation smoking Infections. Patients with other inflammatory skin disorders use of antioxidant and anti-inflammatory drugs patients on treatment for psoriasis

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
measure plasma level of interleukin 38 in all groupsthrough study completion an average of 18 months

level of interleukin 38 will be measured and compared in all groups to asses the relationship between this interleukin and metabolic syndrome in psoriatic patients

Secondary Outcome Measures
NameTimeMethod

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