Effectiveness of PNE on pain after TKA
- Conditions
- Patients with a primary diagnosis of osteoarthritis and scheduled for an elective unilateral total knee arthroplasty (TKA)
- Registration Number
- NL-OMON27550
- Lead Sponsor
- Tergooi hospital, department of Orthopaedics
- Brief Summary
.A.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 76
•Patients 18 years or older
•Symptomatic knee osteoarthritis according to the American College of Rheumatology classification criteria (Wu et al, 2005). Radiographic disease severity will be evaluated for each participant (Kellgren-Lawrence 0-4 grading scale).
•Scheduled for an elective unilateral total knee arthroplasty (TKA) no sooner than 2 weeks from the time of recruitment
•Be able to understand and speak Dutch language
•Patient is willing and able to complete scheduled study procedures and follow-up evaluations.
•Provide written informed consent
•Scheduled for revision arthroplasty
•Diagnosis of inflammatory arthritis (i.e. rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosis, ankylosing spondylitis)
• Scheduled for TKA because of a fracture, malignancy or an infection;
•Patient is currently participating in any other surgical intervention studies or pain management studies
•Previous total knee arthroplasty or any other lower limb surgery within the past six months
•Cognitive impairment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary clinical outcome is pain at 3 months after TKA surgery. The Western Ontario and McMaster Universities Osteoarthirits Index (WOMAC-DV), subscale pain, will be used as pain specific instrument.
- Secondary Outcome Measures
Name Time Method 1. Pain levels 12 months after surgery in patiens undergoing TKA <br>2. Physical functioning 3 and 12 months post-operative<br>3. Stiffness 3 and 12 months post-operative<br>4. Health related quality of life 3 and 12 months post-operative<br>5. Attention to pain 3 and 12 months post-operative<br>6. Pain catastrophizing 3 and 12 months post-operative<br>7. Anxiety and depression 3 and 12 months post-operative