study to determine requirement of anesthesia in diabetic patients compared to healthy patients
Phase 2
Completed
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: null- To determine requirement of isoflurane and vecuronium in diabetic patients with or without autonomic neuropathy undergoing elective surgery.
- Registration Number
- CTRI/2010/091/000040
- Lead Sponsor
- ICMR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
ASA physical status I or II
Age 18-60 years
Controlled diabetic patients of > 3 years duration;HbA1C >8
Exclusion Criteria
BMI>28
Any neuromusular disease
Pregnancy
Predicted difficult airway with laryngoscopic tome > 15 secs
History of liver or renal disease
History of alcohol or drug abuseHistory of gastric esophageal reflux disease
High blood pressure or the use of beta blocking agent
Hypersensitivity to any of the frugs to be used
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of Isoflurane required to maintain SE between 40-60 by measuring isoflurane vaporizer before and after anesthesia <br/ ><br>The minimum to maximum amount of MAC isoflurane required to maintain SE between 40-60 <br/ ><br>Total consumption of vecuronium and fentanyl <br/ ><br>Total intraoperative consumption of atropine and ephedrine <br/ ><br>Comparison of the amount of isoflurane and vecuronium consumed in both the groups <br/ ><br>Timepoint: Preoperative <br/ ><br>At the time of induction <br/ ><br>Intraoperative <br/ ><br>Postoperative
- Secondary Outcome Measures
Name Time Method ilTimepoint: Nil