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Acute Effects of Smoking on Airway Dendritic Cells

Not Applicable
Completed
Conditions
Tobacco Use Disorder
Registration Number
NCT00740896
Lead Sponsor
University of Rostock
Brief Summary

Airway dendritic cells control pulmonary immune responses to inhaled particles. It is the aim of the present study to investigate the acute effects of smoking on the number and surface molecule expression of human airway dendritic cells.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
16
Inclusion Criteria
  • Active smoking (at least 10 cigarettes per day)
  • Age > 18 years
Exclusion Criteria
  • Any chronic diseases
  • Any regular medication
  • Any signs or symptoms of an acute infection

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Total number of dendritic cells in bronchoalveolar lavage fluidJune - September 2008
Secondary Outcome Measures
NameTimeMethod
Surface molecule expression on dendritic cells in bronchoalveolar lavage fluidJune - September 2008

Trial Locations

Locations (1)

University of Rostock

🇩🇪

Rostock, Germany

University of Rostock
🇩🇪Rostock, Germany

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