Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation

Active, not recruiting

• Conditions: Atrial Fibrillation

• Registration Number: NCT00599118
• Lead Sponsor: The Cleveland Clinic

Brief Summary

The purpose of this study is to establish a genebank repository of blood samples and data to generate information about the hereditary (genetic) basis of atrial fibrillation.

Detailed Description

Blood samples and data will be collected from subjects with atrial fibrillation and normal controls. The primary aim of future research using these samples is to identify mechanisms and pathogenesis of atrial fibrillation. Through this information, we hope to identify targets for new therapies and improve knowledge and understanding of atrial fibrillation. Identification of disease genes could improve strategies that prevent progression of atrial fibrillation to more persistent disease.

Study Timeline

• Study Start: 2005-08
• Study First Submitted: 2008-01-10
• Study First Submitted QC: 2008-01-11
• Study First Posted: 2008-01-23
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-28
• Last Update Posted: 2024-08-29
• Primary Completion: 2035-12
• Study Completion: 2035-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1300

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Genetic variants associated with atrial fibrillation	Baseline	Genome-wide association study of atrial fibrillation

Trial Locations

Locations (1)

Cleveland Clinical Foundation; 🇺🇸 Cleveland, Ohio, United States