Effect of transcranial direct current stimulation on cognitive function in mild cognitive impairment

Not Applicable

Completed

• Conditions: mild cognitive impairment; Transcranial direct current stimulation, cognitive function&#44

• Registration Number: TCTR20151125002
• Lead Sponsor: Ratchadapiseksompotch Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11-25
• Study Completion: 2016-10-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

MCI patients with
1. Age 45-90 years old
2. TMSE >23/30 and Thai version of the montreal cognitive assessment (MoCA-Thai) <25/30
3. Can participate in research over the period

Exclusion Criteria

1.contraindication to tDCS:
- implanted metal devices
- history of seizure
- using drugs reducing seizure threshold
- disorder of scalp
- history of head surgery
- had been unconscious for more than 15 minutes
2. neurological abnormalities show upper motor neuron signs: spasticity, hypereflexia
3.Neuropsychiatric problems
4. The level of education is lower than the fourth grade
5.using drugs effects cognitive performance; antipsychotic drugs, anticholinergic drugs, antiepileptic drugs
6.drug or alcohol abuse or dependence
7.MCI were treated with the drug during the past three months
8.vision problem that has not been corrected or color blindness

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cognitive function immediate effect, 4th wk, 8th wk Rapid visual information processing (CANTAB test)

Secondary Outcome Measures

Name	Time	Method
cognitive function immediate, 4th week, 8th week Spatial working memory(SWM), Pattern recognition memory(PRM), Delayed matching to sample (DMS),side effect immediate, 4th week, 8th week questionare