Effect of vascular occlusion training on muscle and clinical outcome of patients admitted to the intensive care unit

Not Applicable

Recruiting

• Conditions: Disorders of myoneural junction and muscle in diseases classified elsewhere/comatose patient.

• Registration Number: RBR-2qpyxf
• Lead Sponsor: Centro de Ciências Biológicas e da Saúde da Universidade Federal de São Carlos

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-01-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Forty comatose patients admitted to the Adult Intensive Care Unit (ICU) of Santa Casa de Misericórdia de São Carlos will be included in the study. Inclusion criteria will be individuals aged 18 to 60 years (BARBALHO et al., 2018; DIRKS et al., 2015); Ramsay sedation scale with a score of 6 to 4 (DE JONGHE et al., 2000) or a score of 3 to 6 on the Glasgow coma scale (REITH et al., 2016) and with daily protein intake standardized by ICU medical and nutrition team (BARBALHO et al., 2018).

Exclusion Criteria

Obese patients (body mass index greater than 30 kg / m²); with more than one risk factor for venous thromboembolism (ANDERSON; SPENCER, 2003); using vasoactive drugs; fever; anemia; thrombocytopenia and neurodegenerative and musculoskeletal diseases will not be included in the research. Persistent arrhythmias such as atrial fibrillation; pre-existing atrioventricular block or ventricular tachycardia; recent acute myocardial infarction; provisional or definitive pacemaker; signs of intracranial hypertension; neoplasia under chemotherapy treatment and unconsolidated fracture will be considered criteria for non-inclusion in the study (GEROVASILI et al., 2009).

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevention of muscle atrophy is expected through the method of ultrasound imaging evaluation of the vastus lateralis, rectus femoris and anterior tibialis muscle from the finding of no reduction in muscle thickness and quality.