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The effect of topical Pistacia vera oil on knee joint osteoarthritis

Phase 3
Conditions
Osteoarthritis.
Osteoarthritis of knee
Registration Number
IRCT20180811040759N1
Lead Sponsor
Rafsanjan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
75
Inclusion Criteria

age 45-70 years
diagnosis of knee osteoarthritis according to American College of Rheumatology, approved by rheumatology specialist
the average knee pain within 24 hours is based on the linear-visual pain scale (VAS) between 4 to 7

Exclusion Criteria

Patients with inflammatory diseases (such as lupus, rheumatoid arthritis, history of brucellosis, etc.)
cancer or chronic diseases
symptoms or history of liver or kidney failure
oral corticosteroid consumption during the past 4 weeks
corticosteroid injection in the last 6 months
fever
Consumption of medical herbs continuously
Smoking
pistachio allergy

use of food and drug supplements
Oral use of other analgesics and other compounds effective in treating osteoarthritis up to 10 days before the study
Skin or infectious disease or ulcer at the place of administration
pregnancy

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Knee pain intensity. Timepoint: At the beginning and the end of the study (three months after the beginning of the study). Method of measurement: The linear-visual scale of pain.;Morning stiffness & Patients' function. Timepoint: At the beginning and the end of the study (three months after the beginning of the study). Method of measurement: WOMAC questionnaire.
Secondary Outcome Measures
NameTimeMethod
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