Comparison of letrozole alone with letrozole and N-Acetylcysteine for pregnancy rate in polycystic ovary syndrome patient who were undergoune inductio
Phase 3
Recruiting
- Conditions
- Condition 1: Polycystic ovarian syndrome. Condition 2: pregnancy.Polycystic ovarian syndrome
- Registration Number
- IRCT20180425039418N2
- Lead Sponsor
- Zahedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 162
Inclusion Criteria
presence of two of oligo/involution criteria
clinical or laboratory based evidences of hyperendrogenism and polycystic ovaries in sonography
Exclusion Criteria
thyroid and prolactin dysfunction
tubal abnormalities leading to infertility
medium to severe semen fluid abnormalities of sperm quantity, mobility and shape leading to infertility
presence of cysts(larger than 6 cm), history of asthma and usage of drugs influencing on glucose metabolism within 3 month before study entrance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of pregnancies. Timepoint: since the third day through seventh day after menstruation, 5 mg Letrozole was given to the group of control for 5 days and 5 mg Letrozole and 1200mg N-acetylcycteine were given to the group of intervention. Method of measurement: the structured checklist.
- Secondary Outcome Measures
Name Time Method