Chronic Effect of Isometric Exercise on Blood Pressure in Patients With Controlled Hypertension: a Randomized Clinical Trail
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Bood pressure
研究概览
简要总结
International recommendations support dynamic or isometric strength training as an adjunct to aerobic exercise. Given the lack of consensus, this study aims to evaluate the chronic effects of isometric exercise, performed through handgrip or isometric knee extension, as a hypotensive strategy in adults with hypertension.
详细描述
This study is designed as a randomized, controlled, evaluator-blinded clinical trial, conducted entirely at the Laboratory of Clinical Investigation (LCI) of the Cardiology Institute of Rio Grande do Sul / University Foundation of Cardiology (ICFUC). The project follows all recommendations of the CONSORT Statement.
Male and female participants aged 40 to 70 years, with blood pressure ≥ 120/80 mmHg, will be enrolled. After signing informed consent, participants will complete a questionnaire to assess their habitual physical activity level and will undergo isometric handgrip or isometric knee extension training for 4 weeks. Blood pressure will be assessed at baseline and after the intervention using ambulatory blood pressure monitoring (ABPM).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with controlled hypertension under medication. Sedentary or physically inactive individuals.
排除标准
- •Pregnant women. Unstable angina. Heart failure classified as NYHA class II, III, or IV. Recent cardiovascular event within the last 3 months. Chronic renal insufficiency. Diabetes mellitus. History of malignant disease with a life expectancy of less than 2 years. Orthopedic, physical, or mental limitations that prevent the performance of physical exercise.
研究组 & 干预措施
Control
Isometric handgrip exercise
Small Mass Muscle - isometric handgrip exercise
干预措施: Isometric handgrip exercise (Procedure)
Isometric knee extension exerice
Large Mass Muscule - isometric knee extension exercise
干预措施: Isometric knee extension exercise (Procedure)
结局指标
主要结局
Bood pressure
时间窗: Assessments (systolic/diastolic pressure) will be performed at baseline and after 4 weeks of training (post-intervention).
Bood pressure (systolic and diastolic) measured by Ambulatory Blood Pressure Monitoring
次要结局
未报告次要终点
研究者
Patricia Caetano
PhD student
Instituto de Cardiologia do Rio Grande do Sul