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Clinical Trials/ISRCTN13837507
ISRCTN13837507
Active, Not Recruiting
N/A

The assessment of left ventricular function in septic shock; comparison of ejection fraction measurement (both by two dimensional and three dimensional echocardiography), global longitudinal strain, high sensitivity troponin and pro NtBNP.

Portsmouth Hospitals NHS Trust0 sites118 target enrollmentDecember 7, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
eft ventricular function in septic shock
Sponsor
Portsmouth Hospitals NHS Trust
Enrollment
118
Status
Active, Not Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 7, 2020
End Date
February 29, 2024
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. Aged 18\-85 years inclusive
  • 2\. Sepsis or septic shock (defined by Third International Consensus Definitions for Sepsis and Septic Shock)
  • 3\. Admission to the Intensive Care Unit (ICU)
  • 4\. Consent to inclusion or favourable opinion for inclusion from consultee

Exclusion Criteria

  • 1\. Pregnancy or complications thereof
  • 2\. End\-Stage Renal Failure (ESRF) requiring dialysis, or Chronic Kidney Disease (CKD) with eGFR \<30 ml/min
  • 3\. Cardiac transplant recipient
  • 4\. Uncorrected valvular dysfunction (graded as moderate or severe)
  • 5\. Known structural heart disease
  • 6\. Pre\-existing cardiomyopathy with bundle block on electrocardiogram (ECG)
  • 7\. Previous cardiac valve replacement
  • 8\. Post\-operative within last 7 days
  • 9\. Atrial fibrillation/flutter or frequent ventricular ectopic beats during image acquisition
  • 10\. Death likely within 24 h in the opinion of the assessing clinician

Outcomes

Primary Outcomes

Not specified

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