The assessment of left ventricular function in septic shock; comparison of ejection fraction measurement (both by two dimensional and three dimensional echocardiography), global longitudinal strain, high sensitivity troponin and pro NtBNP.

Portsmouth Hospitals NHS Trust0 个研究点目标入组 118 人开始时间: 2020年12月7日最近更新: 2023年5月22日

适应症

试验速览

暂无简介。

•1. Aged 18-85 years inclusive
•2. Sepsis or septic shock (defined by Third International Consensus Definitions for Sepsis and Septic Shock)
•3. Admission to the Intensive Care Unit (ICU)
•4. Consent to inclusion or favourable opinion for inclusion from consultee

•1. Pregnancy or complications thereof
•2. End-Stage Renal Failure (ESRF) requiring dialysis, or Chronic Kidney Disease (CKD) with eGFR <30 ml/min
•3. Cardiac transplant recipient
•4. Uncorrected valvular dysfunction (graded as moderate or severe)
•5. Known structural heart disease
•6. Pre-existing cardiomyopathy with bundle block on electrocardiogram (ECG)
•7. Previous cardiac valve replacement
•8. Post-operative within last 7 days
•9. Atrial fibrillation/flutter or frequent ventricular ectopic beats during image acquisition
•10. Death likely within 24 h in the opinion of the assessing clinician

发起方