Comparison of circumferential pulmonary vein isolation alone versus linear ablation in addition to circumferential pulmonary vein isolation for catheter ablation in persistent atrial fibrillation: Prospective randomized controlled trial
Not Applicable
Active, not recruiting
- Conditions
- Diseases of the circulatory system
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 220
Inclusion Criteria
1. Patients with persistent Atrial fibrillation (20~80 years)
2. Left Atrium diameter <55mm
3. patients possible to anticoagulation and anti arrhythmic drug
Exclusion Criteria
1. Structural cardiac disease
2. severe renal dysfunction or Contraindication to brain perfusion CT
3. MAZE surgery for Atrial Fibrillation
4. Catheter ablation history for Atrial Fibrillation
5. active internal bleeding
6. Impossible to anticoagulation or antiarrhythmic drug
7. valvular Atrial Fibrillation (Mitral Atresia > Grade II, Mechanical valve, Mitral valve replacement)
8. Patients with severe medical disease
9. Expected survival < 1 year
10. Severe drug addiction or alcoholics
11. patients determined to be unfit for clinical trial by researchers' judgment
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reoccurrence rate of atrial fibrillation after 12 months of atrial fibrillation procedure
- Secondary Outcome Measures
Name Time Method Treatment time associated with the procedure;complications;length of stay;radiofrequency ablation time