The influence of physical activity for patients with liver cirrhosis

Not Applicable

• Conditions: C06.552.380; liver cirrhosis; liver cirrhosis alcoholic; fatty liver; hepatitis; C06.552.630; C06.552.630.380; C06.552.241

• Registration Number: RBR-54ngrx
• Lead Sponsor: niversidade Federal do Rio de Janeiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-18
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Age over 18 years; Carrier of liver cirrhosis.

Exclusion Criteria

Smoking; coronary disease; presence of hepatocellular carcinoma; use of vasoactive drugs (except propranolol); use of current interferon or in the last 3 months; use of corticosteroids; duration of the infectious condition; upper gastrointestinal bleeding in the last two weeks; pregnant; musculoskeletal injuries; upper digestive endoscopy with medium or large caliber esophageal varices without eradication.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected that the experimental group, submitted to the intervention with physical exercises, will show an improvement in the physical conditioning evaluated by the increase in muscle strength and cardiorespiratory capacity.;Our results confirm the expected primary outcome, by showing an improvement in handgrip strength, in the total training volume and the variables of cardiorespiratory capacity in the experimental group, in the post-intervention moment when compared to the pre-intervention. In the control group, we observed a worsening or a picture of stability concerning the same variables analyzed.

Secondary Outcome Measures

Name	Time	Method
It is expected that with the improvement of the physical condition, the experimental group submitted to physical exercises will improve their perception of quality of life.;Our results confirm the expected secondary outcome, by showing an improvement in the domains of the SF-36 questionnaire on the perception of functional capacity, limitations due to physical aspects, pain, general health status and limitations due to social and emotional aspects, at the time when compared to the pre-intervention moment. In the control group, we did not observe differences concerning the moments of the study.