NCT00333125已完成3 期
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 319
- 主要终点
- Mean Intra-Ocular Pressure (IOP)
研究概览
简要总结
The purpose of this study is to compare the intraocular pressure (IOP)-lowering efficacy and safety of two combination products in patients with open-angle glaucoma or ocular hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 or older.
- •Diagnosis of glaucoma or ocular hypertension.
- •Other protocol-defined inclusion criteria may apply.
排除标准
- •Other protocol-defined exclusion criteria may apply.
研究组 & 干预措施
Travoprost/Timolol
Experimental
干预措施: Timolol Vehicle (Other)
Travoprost/Timolol
Experimental
干预措施: Travoprost 40 mcg/ml + Timolol 5 mg/ml eye drops, solution (DuoTrav) (Drug)
Dorzolamide/Timolol
Active Comparator
干预措施: Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (Cosopt) (Drug)
结局指标
主要结局
Mean Intra-Ocular Pressure (IOP)
时间窗: 6 weeks
次要结局
未报告次要终点
研究者
相似试验
已完成
4 期
Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStentsSubjects With Primary Open-angle Glaucoma (POAG)NCT01252862Glaukos Corporation40
已完成
3 期
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular HypertensionOpen-angle GlaucomaOcular HypertensionNCT00293787Alcon Research156
已完成
4 期
Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive AgentsOpen-angle GlaucomaNCT02873806Glaukos Corporation53
已完成
3 期
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular HypertensionOpen-Angle GlaucomaOcular HypertensionNCT00293800Alcon Research173
已完成
4 期
Two Second-Generation Trabecular Micro-bypass Stents to Treat Glaucoma Subjects on One Hypotensive MedicationOpen Angle GlaucomaNCT02868190Glaukos Corporation57