Effect of chemoradiotherapy on locally advanced cancer of Cardia

Phase 2

Recruiting

• Conditions: Cardia cancer.; Malignant neoplasm of cardia; C16.0

• Registration Number: IRCT20140203016473N12
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients aged between 18 to 80 years old
Confirmed advanced localized cardiac adenocarcinoma (stage T3, T4, T2 with lymph node involvement)
No history of previous chemotherapy and radiotherapy
Proper function of the kidney (serum creatinine = 1.5 mg / dl)
Proper function of the liver (serum bilirubin = 1.5 mg / dl)
Proper function of the bone marrow (neutrophil count> 1500 per microliter, platelet count> 100 thousand and Hb> 10)
Performance Status = 2

Exclusion Criteria

Distant metastasis
Patient dissatisfaction with neoadjuvant therapy
Stages T1 and T2 without lymph node involvement (according to the AJCC staging system)
Peritoneal carcinoma

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The stage of cardiac cancer after chemoradiotherapy intervention. Timepoint: 4 to 6 weeks after the intervention. Method of measurement: Staging of heads based on Tumor, Node, Metastases (TNM) system.