Effect of exercise training on fat distribution in patients with type 2 diabetes

Completed

• Conditions: Type 2 diabetes mellitus; Nutritional, Metabolic, Endocrine; Non-insulin-dependent diabetes mellitus

• Registration Number: ISRCTN26977705
• Lead Sponsor: eiden University Medical Center (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-04-08
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

1. Ages of 18 - 70 years
2. Diagnosis of type 2 diabetes mellitus

Exclusion Criteria

1. Complications of diabetes (retinopathy, neuropathy, nephropathy)
2. Hypertension (systolic blood pressure > 165 mmHg and/or diastolic blood pressure > 95 mmHg)
3. Body mass index (BMI) > 35kg/m2
4. Smoking
5. Cardiac diseases
6. Claustrophobia or any other contra-indication for magnetic resonance imaging (MRI)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Visceral and subcutaneous abdominal fat volume<br>2. Myocardial, myocellular and hepatic triglyceride content<br>3. Epi- and pericardal fat volume

Secondary Outcome Measures

Name	Time	Method
1. Cardiac function<br>2. Anthropometric measures (weight, blood pressure)<br>3. Energy intake and expenditure<br>4. Metabolic parameters (HbA1c, lipid levels from blood plasma)