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临床试验/EUCTR2004-002569-19-GB
EUCTR2004-002569-19-GB进行中(未招募)不适用

The effects of systemic vitamin D administration on production of interleukin-10 by peripheral blood T cells in asthmatics and controls. - Vitamin D Study

Department of Asthma, Allergy and Respiratory Science, GKT School of Medicine, King's College London0 个研究点目标入组 30 人开始时间: 2005年2月17日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Subjects must be aged between 18-65 years and willing and able to give signed consent.
  • Mild Asthmatics:
  • Methacholine PC20 <8mg/ml
  • FEV1 >80% predicted
  • Steroid-resistant asthmatics
  • Never smokers
  • No improvement in FEV1 post 2-week systemic steroid trial
  • FEV1>40% predicted
  • Methacholine PC20 >16mg/ml
  • Non-atopic
  • FEV1 >80% predicted
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) no
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Existing pregnancy or breast-feeding.
  • Subjects with existing hypercalcaemia.
  • Subjects with significant renal impairment (plasma creatinine in excess of normal range).
  • Subjects with existing systemic corticosteriod or therapy with any vitamin D analogue.

研究者

发起方
Department of Asthma, Allergy and Respiratory Science, GKT School of Medicine, King's College London

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