Paravertebral Block (PVB) Combined Pectoral Musculature Blocks for Modified Radical Mastectomy (MRM)
Completed
- Conditions
- Mastectomy, Modified Radical
- Registration Number
- NCT02747992
- Lead Sponsor
- Sun Yat-sen University
- Brief Summary
Previous studies have shown that PVB reduces pain and postoperative nausea and vomiting after breast cancer surgery when used in addition to general anesthesia or sedation. However, major breast cancer surgery involves areas beyond the breast tissue, such as pectoral musculature.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- The American Society of Anesthesiologists (ASA) Physical Status classification I to III
- 20 - 75 years of age
- female gender
Exclusion Criteria
- body mass index (BMI) ≥ 35 kg/m2
- modified radical mastectomy not performed by the single surgeon (Ben Long Yu)
- anesthesia not performed by the single anesthesiologist (Nai Liang Li)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method intraoperative sedation requirement during operation target controlled infusion (TCI) propofol driven by the Schnider model in effect site control titrated to reach conscious sedation defined as Observer Assessment of Alertness/Sedation score of 2 to 3
- Secondary Outcome Measures
Name Time Method time to first request of analgesics postoperative 12 hours postoperative analgesic requirement postoperation to discharge side effects postoperation to within 24 hours after discharge