The Role of Imaging in the Diagnosis of Acute Appendicitis During the COVID-19 Pandemic: a Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 313
- 试验地点
- 1
- 主要终点
- Negative Appendicectomy Rate (NAR)
研究概览
简要总结
This is a retrospective observational study in the form of a cohort study evaluating the use of pre-operative imaging for the diagnosis of acute appendicitis in a tertiary centre during the first and second waves of the COVID-19 pandemic in the United Kingdom. The study group includes all patients who underwent emergency appendicectomy for suspected acute appendicitis between March 2020 and February 2021, while the control group includes all patients who underwent emergency appendicectomy for suspected acute appendicitis between March 2019 and February 2020. The final histology will be used as primary outcome, as the study hypothesis is that increasing the use of pre-operative imaging will reduce the negative appendicectomy rate.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of all ages who underwent emergency appendicectomy (either laparoscopic or open) for suspected acute appendicitis
- •Patients of all ages who underwent partial ileo-caecectomy or right hemicolectomy for suspected acute appendicitis
排除标准
- •Patients who underwent elective interval appendicectomy for a previous appendiceal phlegmon
- •Patients who underwent appendicectomy or right hemicolectomy for appendiceal tumours
- •Patients who underwent diagnostic laparoscopy for suspected acute appendicitis, where the appendix was not removed
结局指标
主要结局
Negative Appendicectomy Rate (NAR)
时间窗: Up to 3 weeks post-operatively (when final Histology is ready)
Number of patients with final histology negative for acute appendicitis
次要结局
- Post-Operative Length of Stay(Assessed on day 30 after the completion of the study)
- Post-Operative Complications Rate(Within 30 post-operative days)
研究者
Dr Gerardo Perrotta
Trust Grade Doctor in General Surgery
University College London Hospitals