Provision of breathing support during delayed cord clamping in preterm infants.

Not Applicable

Completed

• Conditions: Prematurity; Anemia requiring red blood cell transfusion; Intraventricular haemorrage; Reproductive Health and Childbirth - Complications of newborn; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12615001026516
• Lead Sponsor: Middlemore Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-01
• Study Completion: 2021-02-01
• Last Update Posted: 20 September 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Infants born <31 week gestation and undergoing delayed cord clamping (DCC); born by vaginal or caeserean section and deemed not to have regular rhythmic breathing (chest wall movement) after 15sec of DCC.

Exclusion Criteria

Infants born equal or > 31 week gestation, known congenital abnormality, twin-to-twin transfusion syndrome, severe antenatal intrauterine growth restriction (estimated fetal weight <10th customised centile), placental abruption, delivery of placenta and infant simultaneously (en caul), short umbilical cord, obsterician refusal, declined antenatal consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Red blood transfusion rates<br>Assessed by reviewing hospital records of red blood cell transfusions received, number received, age of first transfusion in days. The study centre's red cell transfusion guideline will remain unchanged during the study and guideline adherance will be monitored. Infants transferred to other hospitals for surgery or ongoing care will be excluded from primary outcome analysis as so to avoid differing red cell transfusion guidelines.[From birth to time of discharge from neonatal admission]