Safety and efficacy of sedation with midazolam during bronchoscopy
Not Applicable
- Conditions
- Respiratory disease, which is an indication of flexible bronchoscopy
- Registration Number
- JPRN-UMIN000023619
- Lead Sponsor
- Department of Respiratory Medicine Nagoya University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients with SpO2 <90% in the room air 2. There is a history of severe drug hypersensitivity, including hypersensitivity to midazolam 3. Patients with a neuromuscular disease 4. Patients with acute angle-closure glaucoma 5. Patients with myocardial infarction within-onset 6 weeks 6. Patients with other serious complications 7. Patients whom the attending physician has determined to be inappropriate as a subject of the present study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence rate of hypoxemia during bronchoscopy
- Secondary Outcome Measures
Name Time Method 1. Blood concentrations of midazolam (after the initial dose, after adding administration) 2. MOAA/S scale 3. The bispectral index (BIS) 4. Questionnaire about the sedation 5. Adverse events 6. Correlation between gene polymorphism and efficacy or safety of sedation