The effect of direct urinary catheter replacement among adults with UTI, systemic manifestations and indwelling catheter in comparison with replacement after two days of antibiotics.
Not yet recruiting
- Conditions
- CystitisUrinary tract infectionUTI1000401810046590
- Registration Number
- NL-OMON46399
- Lead Sponsor
- Deventer Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
- Presentation emergency department of the Deventer hospital
- Indwelling catheter >=10 days and indication for replacement of the catheter
- Fever >38,5C
- No other infection found that can be accountable for the fever
- Admission to a ward of DZ
Exclusion Criteria
- Antibiotics <24 hours before presentation
- <18 years
- Patient to unstable to wait for the catheter replacement before the start of antibiotics.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary endpoint of this study is the number of days of hospitalization. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary endpoints targets the clinical effect and the safety of the<br /><br>intervention.<br /><br>The endpoints measuring the clinical effectiveness are *days of fever*<br /><br>The endpoints measuring the safety of the intervention are patient reported<br /><br>side effects, registered complications, ICU admissions, death rate, and<br /><br>recurrence of UTI in 30 days after the intervention. </p><br>
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie UTI progression in catheter-associated infections with systemic manifestations?
How does direct urinary catheter replacement compare to standard antibiotic therapy in managing catheter-associated UTIs with systemic symptoms?
Are there specific biomarkers that predict response to catheter replacement in adults with complicated UTIs and systemic involvement?
What are the potential adverse events associated with early urinary catheter replacement in UTI patients with systemic symptoms?
What combination approaches or alternative interventions show promise in treating catheter-associated UTIs with systemic complications compared to delayed catheter replacement?