NCT06655012招募中不适用
The Muscle Anabolic Response to β2-adrenergic Stimulation
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Power output during sprint testing
研究概览
简要总结
The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion Criteria:
- •Age 18-40
- •Physically active >5 hours a week
- •Maximum oxygen uptake classified as high or very high
排除标准
- •Active smoker currently or within the past 5 years
- •Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
- •Chronic or acute illness deemed by the responsible study physician to affect the test parameters
- •Deviation from the study protocol
- •Lean mass index >21 kg/m²
- •Pregnancy
- •Blood donation during the past 3 months
研究组 & 干预措施
Salmeterol
Experimental
Participants are administered salmeterol from an inhaler device
干预措施: Salmeterol (Drug)
Placebo
Placebo Comparator
Participants are administered placebo from an inhaler device
干预措施: Placebo (Drug)
结局指标
主要结局
Power output during sprint testing
时间窗: Through study completion, an average on 2 weeks
Power output measured in Watts during a sprint on a bike ergometer
次要结局
- Power output during time trial(Through study completion, an average on 2 weeks)
研究者
Morten Hostrup, PhD
Associate Professor
University of Copenhagen
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Physiologic Performance Response to SalbutamolHealthyNCT04615611University of Copenhagen20
Unknown
不适用
cAMP Signaling and Muscle AdaptationsMuscle Hypertrophy in Healthy Young MenNCT02557581University of Copenhagen72
已完成
不适用
Chronic Beta2-adrenergic Stimulation and Cardiac and Skeletal Muscle HypertrophyMuscle Hypertrophy in Healthy Young MenNCT02551276University of Copenhagen42
撤回
早期 1 期
PET Study of a2a Agonist Effects on the Ventricular CSF Clearance of [11C]ButanolHealthy VolunteersNCT04032691Weill Medical College of Cornell University
进行中(未招募)
1 期
Activation of human brown adipose tissue with the use of salbutamolObesity, overweight, lipid- and glucose metabolismMedDRA version: 20.0Level: LLTClassification code 10029885Term: Obesity, unspecifiedSystem Organ Class: 100000004861EUCTR2020-004059-34-NLeiden University Medical Center10
