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临床试验/NCT06655012
NCT06655012招募中不适用

The Muscle Anabolic Response to β2-adrenergic Stimulation

University of Copenhagen1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2024年10月31日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
36
试验地点
1
主要终点
Power output during sprint testing

研究概览

简要总结

The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Inclusion Criteria:
  • Age 18-40
  • Physically active >5 hours a week
  • Maximum oxygen uptake classified as high or very high

排除标准

  • Active smoker currently or within the past 5 years
  • Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
  • Chronic or acute illness deemed by the responsible study physician to affect the test parameters
  • Deviation from the study protocol
  • Lean mass index >21 kg/m²
  • Pregnancy
  • Blood donation during the past 3 months

研究组 & 干预措施

Salmeterol

Experimental

Participants are administered salmeterol from an inhaler device

干预措施: Salmeterol (Drug)

Placebo

Placebo Comparator

Participants are administered placebo from an inhaler device

干预措施: Placebo (Drug)

结局指标

主要结局

Power output during sprint testing

时间窗: Through study completion, an average on 2 weeks

Power output measured in Watts during a sprint on a bike ergometer

次要结局

  • Power output during time trial(Through study completion, an average on 2 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Morten Hostrup, PhD

Associate Professor

University of Copenhagen

研究点 (1)

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