NCT04615611Unknown不适用
Individual beta2-adrenergic Performance Response to Salbutamol
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Sprint performance
研究概览
简要总结
This project aims to investigate the individual physiological response to beta2-adrenergic stimulation with salbutamol on performance-related outcomes
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 to 45 years of age
- •Trained individuals with maximal oxygen uptake above 55 mL/kg/min for men and 50 mL/kg/min for women
- •Body mass index lower than 26
排除标准
- •Allergy towards study drug
- •Unacceptable side effects of the study drug
- •Chronic disease deemed by the MD to impose a risk or severely confound the study outcomes
- •Current smokers
- •Use of prescription medicine
- •Pregnancy
研究组 & 干预措施
salbutamol
Experimental
salbutamol, 800 microgram from metered dose inhaler
干预措施: salbutamol (Drug)
placebo
Placebo Comparator
placebo
干预措施: Placebo (Drug)
结局指标
主要结局
Sprint performance
时间窗: Measured ½ hour after drug administration
Power output during maximal cycling
次要结局
- Cycling endurance performance(Measured ½ hour after drug administration)
- Muscle strength(Measured ½ hour after drug administration)
- Sprint fatigue tolerance(Measured ½ hour after drug administration)
研究者
Morten Hostrup, PhD
Associate Professor
University of Copenhagen
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