Comparative Study Of Nebulised Dexmedetomidine And Nebulised Magnesium Sulphate For Attenuation Of Haemodynamic Response During Laryngoscopy And Intubation
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To compare the hemodynamic effects of Nebulised Dexmedetomidine and Nebulised Magnesium Sulphate on the patient during Laryngoscopy and Intubation.
研究概览
简要总结
Laryngoscopy and Intubation are a crucial part of general anaesthesia in a patient undergoing surgery. Sympathetic stimulation and catecholamine release while performing Laryngoscopy and Intubation leads to hemodynamic changes ,mainly Tachycardia and Hypertension.
Many agents are in use for reducing these hemodynamic changes. We plan to use Dexmedetomidine and Magnesium Sulphate in nebulised form, in 90 patients, ASA grade 1 and 2 undergoing elective surgery who need Endotracheal Intubation.
Our aim will be to compare the hemodynamic changes of these two drugs during Laryngoscopy and Intubation. We will also observe the side effects and complications if any.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA Grade 1 and 2, Age 18-35 years, BMI less than 30, Mallampati grading 1 and 2, Patients undergoing elective surgeries requiring General Anaesthesia with Endotracheal Intubation.
排除标准
- 未提供
结局指标
主要结局
To compare the hemodynamic effects of Nebulised Dexmedetomidine and Nebulised Magnesium Sulphate on the patient during Laryngoscopy and Intubation.
时间窗: Before nebulisation, After nebulisation. | 2, 5, and 10 minutes following Intubation
次要结局
- To observe any side effects and complications related to the drugs.(Intraoperative, Up to 24 hours Post-operatively.)