CTRI/2020/11/029241尚未招募3 期
Comparative evaluation of Dexmedetomidine nebulisation and Ketamine nebulisation as an adjuvant to Lignocaine for awake fiberoptic intubation.
King Georges Medical University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年11月20日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- to assess the ease of intubation
研究概览
简要总结
difficulty in airway management during anaesthesia can lead to severe anaesthesia related morbidity and mortality. awake intubation now has become one of the recommended modality to manage airway that is expected to be difficult. fibreoptic bronchoscopy is a relatively safer method used now for the management of the same.
comparasion between dexmedetomedine and ketamine nebulisation as an adjuvant to lignocaine for awake fiberoptic intubation could bring new insight in the area of awake intubations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with American Society of Anaesthesiology grading of 1 and
- •Patients having Mallampati grading of 3 and 4 and mouth opening less than 2 finger and also patients in whom neck extension is contraindicated.
排除标准
- •patients with any type of AV block, bradycardia, hypotension, ventricular dysfunction, heart failure, coronary disease.
- •patients with nasal pathology and recent epistaxis.
- •allergy to drugs being used in the study patients not giving consent.
结局指标
主要结局
to assess the ease of intubation
时间窗: to assess the ease of intubation using glottic score and cough score during bronchoscopy.
次要结局
- to assess the degree of sedation between two groups using Ramsay sedation score.(to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period.)
研究者
研究点 (1)
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