To compare between nebulisation with dexmedetomidine and nebulisation with Ketamine as an accessory to nebulisation with lignocaine for awake fiberoptic intubation.

Phase 3

Not yet recruiting

Brief Summary: difficulty in airway management during anaesthesia can lead to severe anaesthesia related morbidity and mortality. awake intubation now has become one of the recommended modality to manage airway that is expected to be difficult. fibreoptic bronchoscopy is a relatively safer method used now for the management of the same.

comparasion between dexmedetomedine and ketamine nebulisation as an adjuvant to lignocaine for awake fiberoptic intubation could bring new insight in the area of awake intubations.

Recruitment & Eligibility

Inclusion Criteria

Patients with American Society of Anaesthesiology grading of 1 and 2.
Patients having Mallampati grading of 3 and 4 and mouth opening less than 2 finger and also patients in whom neck extension is contraindicated.

Exclusion Criteria

patients with any type of AV block, bradycardia, hypotension, ventricular dysfunction, heart failure, coronary disease.
patients with nasal pathology and recent epistaxis.
allergy to drugs being used in the study patients not giving consent.

Primary Outcome Measures

Name	Time	Method
to assess the ease of intubation	to assess the ease of intubation using glottic score and cough score during bronchoscopy.

Secondary Outcome Measures

Name	Time	Method
to assess the degree of sedation between two groups using Ramsay sedation score.	to assess the hemodynamic parameters of patient preoperatively, during intubation and during the intra operative period.

Locations (1): King George Medical University
🇮🇳
Lucknow, UTTAR PRADESH, India
King George Medical University
🇮🇳Lucknow, UTTAR PRADESH, India
bhawana sharma
Principal investigator
7407533830
bhawray13@gmail.com