The role of resistant starch in the treatment of insulin resistance

Completed

• Conditions: Topic: Metabolic and Endocrine; Subtopic: Metabolic and Endocrine (all Subtopics); Disease: Metabolic & Endocrine (not diabetes); Nutritional, Metabolic, Endocrine; Insulin resistance

• Registration Number: ISRCTN56997186
• Lead Sponsor: niversity of Surrey (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05-19
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. Non-diabetic
2. No history of cardiovascular, endocrine or gastrointestinal disease
3. Male and female over the age of 18 years
4. Fasting plasma insulin greater than 60 pmol/l

Exclusion Criteria

Not provided at time of registration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Insulin sensitivity measured with hyperinsulinaemic euglycaemic clamp at end of each 8 week intervention.

Secondary Outcome Measures

Name	Time	Method
1. mRNA expression in adipose tissue biopsies taken at end of each 8 week intervention<br>2. Postprandial meal handling and arteriovenous uptake of glucose measured at end of each 8 week intervention