Resistant starch effects in subjects with diabetes

Not Applicable

Completed

• Conditions: Diabetes; Metabolic and Endocrine - Diabetes; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12621001382864
• Lead Sponsor: niversidad Juárez Autónoma de Tabasco

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-05-30
• Study Start: 2021-10-11
• Last Update Posted: 18 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

1. Subjects with type 2 diabetes (T2D) previously diagnosed according to the American Diabetes Association.
2. Aged 25-60. Both males and females.
3. Body Mass Index (BMI) > 25 kg/m2.
4. Type 2 diabetic with glycosylated hemoglobin (HbA1c) over 6.5%, Under treatment with oral medication such as glibenclamide and/or metformin or lifestyle control.

Exclusion Criteria

1.Smoking or alcohol intake.
2.Presence of cardiovascular, renal, hepatic or gastrointestinal disease (Crohn´s disease, colitis, gastroenteritis, celiac disease, short bowel syndrome).
3.Use of any medication with insulin, glitazones, DPP4 inhibitors, GLP -1 analogues, or other drugs that alter the absorption of monosaccharides, such as acarbose.
4.Have some form of psychiatric treatment.
5.Pregnant or breast-feeding females.
6.Practice physical exercise for more than 4 h a week.
7.Have non-permeable veins.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glycemic variability as measured by 4-day continuous glucose monitoring. 24h Incremental Area Under Curve (24h-iAUC), 24h Mean Blood glucose (24h-MBG)., Standard deviation (SD), Coefficient of Variation CV%, mean amplitude of glycaemic excursion (MAGE), Continuous overall Net Glycemic Action (CONGA) and Mean Absolute Glucose (MAG).<br><br>[The continuous glucose monitoring will begin on day 1 before the administration of the supplements and will be extended until day 5 of the experimental period. Determinations of the intersticial glucose concentrations will be determined every 5 min by this tool. <br>]