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The Role of Blood Flow Restriction Therapy in Postop Rehabilitation of Foot and Ankle Injuries

Not Applicable
Withdrawn
Conditions
Fracture of Foot
Interventions
Procedure: BFR+NMES at therapeutic level
Procedure: BFR+NMES at sub therapeutic level
Registration Number
NCT05844280
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

The purpose of the study is to determine the role of blood flow restriction (BFR) + neuromuscular electrical stimulation (NMES) in improving post-operative physical therapy and recovery after ankle fracture surgery. We expect to see improved muscle strength, less muscle wasting, and improved functional recovery after surgery when making these additions to routine post-operative (postop) physical therapy protocols.

Detailed Description

Few studies have examined BFR in patients sustaining operative foot and ankle injuries. Due to the weight bearing limitations and prolonged immobilization following these injuries, patients often experience increased time away from work and delays with return to sport. These factors are responsible for the rapid muscle atrophy that occurs in the immediate post injury period because of immobility and disuse. Recently, blood flow restriction (BFR) therapy has been shown to be effective in improving muscle strength and preventing atrophy when combined with low load resistance training physical therapy programs.7,8 Neuromuscular electrical stimulation (NMES) is an adjunctive agent that has been show to augment the effects of BFR alone.4 The null hypothesis is that a 2 week BFR + NMES + low load resistance training program in patients age \>= 18 recovering from foot and ankle surgery will have no effect on short term (2 weeks postop) lower extremity muscle hypertrophy or atrophy, patient pain and satisfaction, or functional recovery after foot and ankle surgery.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
28
Inclusion Criteria
  • isolated, closed low-energy rotational ankle fracture without prior surgery or implants to injured area
Exclusion Criteria
  • history of Deep Vein Thrombosis in affected extremity
  • history of significant cardiac disease defined as a recent stent placement in past
  • history of peripheral arterial disease
  • history of sickle cell disease
  • history of coagulopathy
  • presenting to surgery >14 days after injury

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Treatment GroupBFR+NMES at therapeutic levelreceiving physical therapy with BFR+NMES devices used at settings that are deemed by prior studies to be therapeutic
Control GroupBFR+NMES at sub therapeutic levelreceiving physical therapy with BFR+NMES devices used at sub-therapeutic levels
Primary Outcome Measures
NameTimeMethod
Assess for calf muscle atrophy as measured by calf circumference2 weeks postop

Calf circumference will be measured using a measuring tape

Assess for calf muscle atrophy as measured by hand held dynamometry2 weeks postop

Hand held Dynamometry will be used to measure the length-tension relationship of the muscle in pounds

Secondary Outcome Measures
NameTimeMethod
Patient tolerance of the BFR treatment using the Visual Analogue Pain Scale.2 weeks postop

The Visual Analogue Pain Scale is used during the beginning, midpoint, and end of a session.

This scale ranges from 0-10 which 0 being "no pain" and 10 being "worst pain"

Patient tolerance of the BFR treatment using the the Borg Rating of Perceived Exertion f2 weeks postop

The Borg Rating of Perceived Exertion will be used for each session and exercise.

This rating ranges from 6-20 with 6 being no exertion at all, and 20 being maximum effort

Trial Locations

Locations (1)

University of Alabama at Birmingham

🇺🇸

Birmingham, Alabama, United States

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