Effect of Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy

Not Applicable

Completed

• Conditions: Prostate Cancer
• Interventions: Procedure: Total intravenous anesthesia; Procedure: Inhalation anesthesia

• Registration Number: NCT03271502
• Lead Sponsor: Asan Medical Center

Brief Summary

The purpose of this study was to evaluate the difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia in patients undergoing robot-assisted laparoscopic prostatectomy.

Detailed Description

The purpose of this study was to evaluate the difference between the optic nerve sheath diameter measured during total intravenous anesthesia with propofol and remifentanil and the optic nerve sheath diameter measured during inhalation anesthesia with sevoflurane and remifentanil in patients undergoing robot-assisted laparoscopic prostatectomy.

Study Timeline

• Study First Submitted: 2017-08-31
• Study First Submitted QC: 2017-08-31
• Study Start: 2017-09-04
• Study First Posted: 2017-09-05
• Primary Completion: 2017-09-26
• Status Verified: 2017-10
• Study Completion: 2017-10-01
• Last Update Submitted: 2017-10-25
• Last Update Posted: 2017-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 36

Inclusion Criteria

Patients who have undergone a robot-assisted laparoscopic prostatectomy with a prostate cancer and who are 20 years of age or older and under 80 years of age and who agree to participate in this study.

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Exclusion Criteria

Patients with a history of cerebral hemorrhage or cerebral infarction, Patients < 20 years of age, Patients ≥ 80 years of age, Patients with unexpected hemodynamic instability during surgery, Failure to measure optic nerve sheath diameter.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Total intravenous anesthesia	Total intravenous anesthesia	Total intravenous anesthesia with propofol and remifentanil
Inhalation anesthesia	Inhalation anesthesia	Inhalation anesthesia with sevoflurane and remifentanil

Primary Outcome Measures

Name	Time	Method
Difference in optic nerve sheath diameter	60 minutes after pneumoperitoneum and steep Trendelenburg position	Difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia

Secondary Outcome Measures

Name	Time	Method
Difference in optic nerve sheath diameter	5 minutes after pneumoperitoneum and steep Trendelenburg position	Difference between the optic nerve sheath diameter measured during total intravenous anesthesia and the optic nerve sheath diameter measured during inhalation anesthesia

Trial Locations

Locations (1)

Asan Medical Center; 🇰🇷 Seoul, Korea, Republic of