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Burden and sequelae of influenza and SARSCoV-2 among adults a multisite study in India

Not Applicable
Conditions
Health Condition 1: U071- COVID 19 virus identifiedHealth Condition 2: J09-J18- Influenza and pneumoniaHealth Condition 3: J20-J22- Other acute lower respiratory infections
Registration Number
CTRI/2023/05/052797
Lead Sponsor
AIIMS , NEW DELHI
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Admitted patients screened within 24 hours of admission

Onset of fever (>= 38 C°) and cough within last 10 days of admission

Willing to give consent for storage of blood samples and telephonic/physical follow up

Exclusion Criteria

Cases who have been admitted for more than 48 hours for the current episode at the time of screening will be excluded to avoid SARI cases due to hospital acquired infection

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Influenza and SARS Co-V positivity among adult SARI admission in tertiary and secondary hospital; <br/ ><br>2. Incidence of SARI in rural and urban community and its health care seeking <br/ ><br>3. Percentage of patients with diagnostic investigations and treatment options <br/ ><br>4. Mean total cost of treatment of SARI/INFLUENZA / COVID admissions <br/ ><br>5. Cumulative incidence of sequelae in subjects hospitalized with influenza or SARScov2 <br/ ><br>6. Incidence of influenza and SARSCoV2 infection among healthcare workers <br/ ><br>7.Vaccination use hesitancy among healthcare workers and its determinantsTimepoint: Continuous data collection
Secondary Outcome Measures
NameTimeMethod
1. Proportions of enrolled SARI patients with different outcomes i.e. death or, ICU admission or, discharge and their predictors <br/ ><br>2. Identification of risk factors for development of specific sequelae & re-infection <br/ ><br>3. QoL of Patients with sequelae <br/ ><br>4. Absenteeism due to respiratory infections in HCWTimepoint: Continuous data collection
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