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Eye Movements Recording Using a Mobile : Comparison to Standard Video-oculography in Young Athletes

Completed
Conditions
Healthy
Interventions
Other: eVOG (Mobile VideoOculoGraphy)
Registration Number
NCT05211752
Lead Sponsor
Association de Recherche Bibliographique pour les Neurosciences
Brief Summary

This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on smartphones or tablets, to measure eye movements) with measurements from the standard video-oculography device (Eye-Tracker®T2), in young athletes.

Detailed Description

e-VOG Young athletes is a collaborative study between the Memory Center of the Rainier III Center (Princess Grace Hospital, Monaco), the Neurology Department of Nice University Hospital (France), and the AS Monaco Football Academy medical team.

Memory Center of the Rainier III Center is expert in eye-tracking and is equipped with a standard video-oculography device (Eye-Tracker®T2), which records eye movements at a high frequency and measures saccades parameters (latency, speed, amplitudes etc...).

e-VOG is a mobile application, home-developed by the Neurology Department team of Nice University Hospital, to measure eye movements.

Based on literature, investigators hypothesize that video-oculography could integrate assessment protocols for head trauma occurring during sports practice. The nomadic nature of the e-VOG application would make possible to assess oculomotor behaviors to a subject who has just suffered a trauma and who is suspected of having a concussion.

From this perspective, it seems necessary to firstly validate baseline values of the e-VOG application in a population of athletes without major health problems, and who have not presented concussion.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
46
Inclusion Criteria
  • Young Athletes from AS Monaco Football Academy
  • referred by AS Monaco Medical Team to perform a video-oculography (Eye-Tracking) examination as part of routine care.
  • covered by a health insurance system
  • volunteer, able to give free, informed and written consent.
  • For minors: whose holder of parental authority has given their written consent to participate following the information given by investigator.
Exclusion Criteria
  • General anaesthesia within 3 months.
  • Head trauma within 3 months
  • Neurological, ophthalmological or general pathology preventing the realization of a video-oculography examination.
  • Oculomotor abnormality detectable on clinical examination by the neurologist prescribing the standard video-oculography examination.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Healthy young athletes (Eye-Tracker®T2 + e-VOG)eVOG (Mobile VideoOculoGraphy)Subjects who first perform standard video-oculography assessment, followed by e-VOG digital assessment.
Healthy young athletes (e-VOG + Eye-Tracker®T2)eVOG (Mobile VideoOculoGraphy)Subjects who first perform e-VOG digital assessment, followed by the standard video-oculography assessment.
Primary Outcome Measures
NameTimeMethod
Oculomotor profiles concordanceDay 0

Analyze of the concordance of the profiles obtained between the e-VOG digital assessment and the standard video-oculography assessment.

Evaluation criteria: For each assessment, patients will be classified according to the number of oculomotor abnormality observed (based on identified parameters assessments: latency / speed / gain / altered ocular pursuits / fixation disorders / presence of internuclear ophthalmoplegia), in accordance with the literature standards.

Secondary Outcome Measures
NameTimeMethod
Velocity during horizontal reflex saccadesDay 0

Measure of Velocity during an horizontal reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device.

Evaluation criteria: velocity (mean and peak velocity) in °/s.

Impairment of vertical smooth pursuitDay 0

Highlight Impairment of horizontal smooth pursuit with e-VOG Compared to standard video-oculography device.

Evaluation criteria: presence/absence of saccade and perturbation.

Latency during horizontal reflex saccadesDay 0

Measure of Latency during an horizontal reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device.

Evaluation criteria: latency (reaction time in ms).

Latency during vertical reflex saccadesDay 0

Measure of Latency during a vertical reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device.

Evaluation criteria: latency (reaction time in ms).

Latency during horizontal voluntary saccadesDay 0

Measure of Latency during an horizontal volontary saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device.

Evaluation criteria: latency (reaction time in ms).

Inhibition capacityDay 0

Measure of inhibition capacity performance during an antisaccades" paradigm with e-VOG Compared to the one evaluated with standard video-oculography device.

Evaluation criteria: percentage of errors.

Internuclear ophthalmoplegia (INO) detectionDay 0

Highlight presence/absence of INO with e-VOG Compared to standard video-oculography device.

Evaluation criteria: INO is present if calculated ratio of abducting to adducting eye movement (both mean and peak velocity) is \>1.

Fixations impairments detectionDay 0

Highlight presence/absence of Fixations impairments with e-VOG Compared to standard video-oculography device.

Evaluation criteria: presence/absence/frequency of square wave-jerks, nystagmus, flutters.

Velocity during vertical reflex saccadesDay 0

Measure of Velocity during a vertical reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device.

Evaluation criteria: velocity (mean and peak velocity) in °/s.

Impairment of horizontal smooth pursuitDay 0

Highlight Impairment of horizontal smooth pursuit with e-VOG Compared to standard video-oculography device.

Evaluation criteria: presence/absence of saccade and perturbation.

Trial Locations

Locations (1)

Centre Mémoire / Centre de Gérontologie Clinique Rainier III / Princess Grace Hospital

🇲🇨

Monaco, Monaco

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