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Clinical Trials/NCT03261544
NCT03261544
Recruiting
Not Applicable

Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

Duke University1 site in 1 country50 target enrollmentNovember 10, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcoma
Sponsor
Duke University
Enrollment
50
Locations
1
Primary Endpoint
The Musculoskeletal Tumor Society (MSTS) score
Status
Recruiting
Last Updated
8 months ago

Overview

Brief Summary

The purpose of this study is to assess the functional outcomes in patients undergoing proximal femur resection and reconstruction with an endoprosthesis, based on the abductor muscle repair technique. The investigators hypothesize that those patients who receive reattachment of the abductors directly into the prosthesis will have better functional outcomes overall. Furthermore, the investigators plan to develop a simple, cost effective, and reproducible method to assess abductor function at clinical post-operative visits through plain radiographs.

Detailed Description

Patients treated for proximal femur replacements at Duke University Medical Center by Orthopaedic Oncology trained surgeons. The Duke DEDUCE database will be used to identify retrospective patients using the above mentioned CPT codes. Individual chart review of the electronic medical record will then be used to identify those receiving a proximal femur replacement. Maximum number of charts to be reviewed in the study will be 300. Of these 300 charts, the investigators plan to consent 25 subjects who have return appointments scheduled. The investigators also plan to consent 25 preoperative patients, for a total of 50 subjects.

Registry
clinicaltrials.gov
Start Date
November 10, 2017
End Date
November 1, 2028
Last Updated
8 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Has undergone or is scheduled for proximal femur replacement by an Ortho Oncology surgeon

Exclusion Criteria

  • Non-ambulatory before or after the procedure
  • Subjects who, in the opinion of the investigator, have not or likely will not complete at least some portion of the investigator's recommended follow-up

Outcomes

Primary Outcomes

The Musculoskeletal Tumor Society (MSTS) score

Time Frame: up to 24 months postoperatively

The Musculoskeletal Tumor Society (MSTS) score of extremity function. The total score ranges from 0 to 30, with higher scores indicating better function.

Harris Hip Score

Time Frame: up to 24 months postoperatively

The Harris Hip Score (HHS) is a clinician-based outcome measure that is frequently used for the evaluation of patients following a Total Hip Arthroplasty (THA). The survey has ten questions and scores ranging from 0-100, with higher scores representing less dysfunction and better outcomes.

Number of patients with an implant-related complication as reported on the adverse event form upon participation completion.

Time Frame: up to 24 months postoperatively

The adverse event form records the occurence of implant-related complications that occur during study participation.

Secondary Outcomes

  • Gait Analysis as reported on the study's case report form(up to 24 months postoperatively)

Study Sites (1)

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