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Surgical Treatment of Hip Fractures Under Peripheral Regional Anesthesia

Registration Number
NCT04005404
Lead Sponsor
Helios Research Center
Brief Summary

The study investigates whether treatment of proximal femoral fractures is possible using a peripheral regional anesthesia technique.

Detailed Description

The study investigates whether treatment of proximal femoral fractures is possible using a peripheral regional anesthesia technique.

After positioning on the non-fractured side, a double injection technique is used (dual guidance concept: nerve stimulation and sonography).

The injections are performed parasacrally (blockade of the sacral plexus under the piriformis muscle) and lumbar paravertebrally (psoas compartment block and transmuscular quadratus lumborum block). Per block 20 ml ropivacaine 0.375% is administered (total dose: 225mg ropivacaine).

The study examines the success rate (rate of successfully performed nerve blockade; need for supplemental medication: sufentanil and/or propofol; conversion rate to general anesthesia), circulatory stability (need for application of ephedrine or norepinephrine) and side effects.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
80
Inclusion Criteria
  • proximal femoral fracture
  • older then 18 years
  • written informed consent
Exclusion Criteria
  • local or systematic inflammation
  • allergy to ropivacaine
  • participate in other studies
  • body mass index over 35
  • periprosthetic fractures

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
neck femur fracturesRopivacaine (sciatic nerve block)geriatric patients with neck of femur fracture who have consented to the study intervention
neck femur fracturesRopivacaine (lumbar plexus block L2-L4)geriatric patients with neck of femur fracture who have consented to the study intervention
intertrochanteric femoral fracturesRopivacaine (sciatic nerve block)geriatric patients with intertrochanteric femoral fracture who have consented to the study intervention
intertrochanteric femoral fracturesRopivacaine (lumbar plexus block L2-L4)geriatric patients with intertrochanteric femoral fracture who have consented to the study intervention
subtrochanteric femoral fracturesRopivacaine (sciatic nerve block)geriatric patients with subtrochanteric femoral fracture who have consented to the study intervention
subtrochanteric femoral fracturesRopivacaine (lumbar plexus block L2-L4)geriatric patients with subtrochanteric femoral fracture who have consented to the study intervention
intertrochanteric femoral fracturesRopivacaine (lumbar plexus block Th12-L1)geriatric patients with intertrochanteric femoral fracture who have consented to the study intervention
neck femur fracturesRopivacaine (lumbar plexus block Th12-L1)geriatric patients with neck of femur fracture who have consented to the study intervention
subtrochanteric femoral fracturesRopivacaine (lumbar plexus block Th12-L1)geriatric patients with subtrochanteric femoral fracture who have consented to the study intervention
Primary Outcome Measures
NameTimeMethod
Success Rate (Conversion to General Anesthesia)during surgery

number of participants with need for conversion to general anesthesia

Success Rate (Supplemental Medication)during surgery

number of participants with need for supplemental analgesic medication (sufentanil)

Secondary Outcome Measures
NameTimeMethod
Circulation Stabilityduring surgery

number of participants with need for application of ephedrine and/or norepinephrine

Trial Locations

Locations (1)

Helios Medical Center Schwerin, Department of Anesthesiology

🇩🇪

Schwerin, Mecklenburg-Vorpommern, Germany

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