NCT01192009已完成不适用
Leucine and Skeletal Muscle Disuse: Clinical Anti-Atrophic Effectiveness and Related Mechanisms
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Skeletal muscle structure (cross-sectional area)
研究概览
简要总结
Leucine supplementation is widely known for promoting strong influence on skeletal muscle remodeling. This study aims to evaluate the effect of leucine supplementation on disuse-induced skeletal muscle atrophy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of anterior cruciate ligament injury
- •Physically active
- •Must be able to swallow tablets
- •Non-smokers
- •Do not use nutritional supplements
排除标准
- •Post-surgical complications
结局指标
主要结局
Skeletal muscle structure (cross-sectional area)
时间窗: 2 weeks
次要结局
- Molecular signalling pathways (hypertrophy, atrophy, and inflammation)(2 weeks)
研究者
Humberto Nicastro
PhD
University of Sao Paulo
研究点 (2)
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