Ocular Surface Dry Eye Microbiome

• Conditions: Dry Eyes

• Registration Number: NCT02306668
• Lead Sponsor: University of Washington

Brief Summary

The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02
• Status Verified: 2014-12
• Study First Submitted: 2014-12-01
• Study First Submitted QC: 2014-12-02
• Last Update Submitted: 2014-12-02
• Study First Posted: 2014-12-03
• Last Update Posted: 2014-12-03
• Primary Completion: 2016-12
• Study Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• dry eye syndrome with OSDI score greater than 60
• control group with OSDI score less than 30

Exclusion Criteria

• recent history of contact lens wear
• use of topical antibiotics or prescription eye medication in past 6 months
• penetrating ocular surgery in the last 12 months
• age less than 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Identification of bacteria or fungus from conjunctival swab	1 month

Trial Locations

Locations (1)

UW Medicine Eye Institute; 🇺🇸 Seattle, Washington, United States