Interactions Between Environmental Exposures and Gut Microbiota in Early Life

Recruiting

• Conditions: Infant Development

• Registration Number: NCT06479928
• Lead Sponsor: Peking University People's Hospital

Brief Summary

Recruit the mothers and their infants who bron in Peking University People's Hospital from 2023 to 2026, to evaluate the interaction between environmental exposure and gut microbiota.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-07-01
• Study First Submitted: 2024-06-24
• Study First Submitted QC: 2024-06-24
• Study First Posted: 2024-06-28
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-20
• Last Update Posted: 2024-07-23
• Primary Completion: 2026-12-01
• Study Completion: 2026-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 756

Inclusion Criteria

1. Pregnant woman

   • aged 20-40 years old
   • natural conception
   • single pregnancy
   • gestational age ≥36 weeks

2. Newborn

   • normal Apgar score
   • no serious congenital diseases

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arsenic levels and Gut microbiota	Pregnancy (12, 24, 36 weeks) and infants (born, 1 week, and 1, 3, 6, 12, 24 months)	Arsenic levels in biological samples; gut microbiota and metabolites in stools.

Trial Locations

Locations (1)

The Peking University People's Hospital; 🇨🇳 Beijing, China