Mean Platelet Volume and TXA2 Levels in Patients With Polycystic Ovary Syndrome (PCOS)

Completed

• Conditions: Polycystic Ovary Syndrome

• Registration Number: NCT01538602
• Lead Sponsor: AGUNCO Obstetrics and Gynecology Centre

Brief Summary

Polycystic ovary syndrome (PCOS)is closely associated with insulin resistance and hyperinsulinemia as well as with increased incidence in diabetes, hypertension, dyslipidemia and atherosclerosis. Indeed, subjects with PCOS were reported to carry an increased long-term cardiovascular risk, among others. Aiming to correlate the mean platelet volume, the thromboxane A2 level and the PCOS, an observational study was planned. Clinical evaluation of metabolic outcomes in PCOS patients is compared to a placebo group.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-02
• Study First Submitted: 2012-02-21
• Study First Submitted QC: 2012-02-23
• Last Update Submitted: 2012-02-23
• Study First Posted: 2012-02-24
• Last Update Posted: 2012-02-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• Women fulfilled two out of three diagnostic criteria for PCOS

Exclusion Criteria

• Pre-existing secondary endocrine disorders
• History of hypertension, diabetes mellitus or cardiovascular disorders
• Pharmacologic treatment in the last 6 months before entering the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean platelet volume
Thromboxane A2

Trial Locations

Locations (1)

Istituto di Patologia Ostetrica e Ginecologica; 🇮🇹 Catania, Italy