Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity

Completed

• Conditions: Polycystic Ovary Syndrome

• Registration Number: NCT01382576
• Lead Sponsor: Gulhane School of Medicine

Brief Summary

In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).

Detailed Description

ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.

Study Timeline

• Study Start: 2010-01
• Status Verified: 2010-12
• Primary Completion: 2010-12
• Study Completion: 2010-12
• Study First Submitted: 2011-06-10
• Study First Submitted QC: 2011-06-24
• Study First Posted: 2011-06-27
• Last Update Submitted: 2012-03-09
• Last Update Posted: 2012-03-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 78

Inclusion Criteria

• Absence of significant abnormalities on physical examination except hirsutism
• no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
• normal thyroid function and prolactin level
• absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease

Exclusion Criteria

• Pregnant
• ovarian tumors
• congenital adrenal hyperplasia or BMI greater than 30 kg/m2

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Gulhane School of Medicine Etlik; 🇹🇷 Ankara, Turkey